Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595132 | 0.88 | PARP1 (0.31) | MAPK1PARP1 | |
| SCHEMBL6634675 | 0.83 | MAPK1 (0.38) | MAPK1GAAALDH1A1NFKB1NFKB2 | |
| SCHEMBL28345166 | 0.81 | CHRNB2 (0.39) | MAPK1KMT2A | |
| SCHEMBL567797 | 0.81 | CHRNB2 (0.39) | MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL653032 | 0.79 | CHRNB2 (0.38) | KMT2A | |
| Hydrochloric Acid SCHEMBL22999868 | 0.78 | CHRNB2 (0.37) | KMT2A | |
| SCHEMBL28780551 | 0.77 | — | — | |
| SCHEMBL415009 | 0.77 | MAPT (0.43) | GAAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL443973 | 0.75 | MAPT (0.44) | GAAALDH1A1KMT2A | |
| SCHEMBL4662681 | 0.75 | HTR2C (0.50) | MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976337-A1 | 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS | Suven Life Sciences Limited (IN) | 2016-01-27 | — | — | EP | disclosed |
| CN-105001225-A | Heterocyclic modulators of lipid synthesis | 3 V BIOSCIENCES INC | 2015-10-28 | — | — | CN | disclosed |
| CN-103561576-B | Heterocyclic modulators of lipid synthesis | 3 V BIOSCIENCES INC | 2015-07-22 | — | — | CN | disclosed |
| CN-103079566-B | Heterocyclyl compounds as histamine H3 receptor ligands | SUVEN LIFE SCIENCES LTD | 2015-06-17 | — | — | CN | disclosed |
| WO-2014147636-A1 | 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS | SUVEN LIFE SCIENCES LIMITED (IN) | 2014-09-25 | — | — | WO | disclosed |