Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096533 | 0.86 | POLB (0.35) | POLBSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16096245 | 0.85 | POLB (0.34) | POLBSMN1; SMN2ALDH1A1ALOX12NPSR1 | |
| SCHEMBL16098234 | 0.80 | CYP1A2 (0.46) | POLBSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16096306 | 0.80 | CYP1A2 (0.40) | POLBSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16097685 | 0.76 | TP53 (0.43) | POLBSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16096554 | 0.76 | TP53 (0.41) | POLBSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16098692 | 0.75 | KDM4E (0.50) | POLBSMN1; SMN2CYP1A2ALDH1A1LMNA | |
| SCHEMBL16098693 | 0.75 | KDM4E (0.50) | POLBSMN1; SMN2CYP1A2ALDH1A1LMNA | |
| SCHEMBL16096810 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL16096168 | 0.74 | ALDH1A1 (0.36) | SMN1; SMN2CYP1A2CYP3A4CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |