SCHEMBL16098079

SCHEMBL16098079

CCCCCCCCN1C=CN(c2cccc3ccccc23)C1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.42
CNR1 P21554 5/20 0.39
CNR2 P34972 5/20 0.39
TLR8 Q9NR97 2/20 0.38
KDM4E B2RXH2 3/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 2/20 0.37
SLC6A3 Q01959 1/20 0.37
ELANE P08246 1/20 0.37
NPC1 O15118 2/20 0.36
GAA P10253 2/20 0.36
HTT P42858 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29527198 1.00 DPP4 (0.42) DPP4CNR1CNR2TLR8KDM4E
SCHEMBL29526691 1.00 DPP4 (0.42) DPP4CNR1CNR2TLR8KDM4E
SCHEMBL16098365 1.00 DPP4 (0.42) DPP4CNR1CNR2TLR8KDM4E
Iodide SCHEMBL29527142 0.99 DPP4 (0.41) DPP4CNR1CNR2TLR8KDM4E
Iodide SCHEMBL29526714 0.99 DPP4 (0.41) DPP4CNR1CNR2TLR8KDM4E
Bromide SCHEMBL17766599 0.99 DPP4 (0.41) DPP4CNR1CNR2TLR8KDM4E
Bromide SCHEMBL29526851 0.99 DPP4 (0.41) DPP4CNR1CNR2TLR8KDM4E
Bromide SCHEMBL17766639 0.99 DPP4 (0.41) DPP4CNR1CNR2TLR8KDM4E
Bromide SCHEMBL29526881 0.99 DPP4 (0.41) DPP4CNR1CNR2TLR8KDM4E
Iodide SCHEMBL17766624 0.99 DPP4 (0.41) DPP4CNR1CNR2TLR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2976330-B1 NEW FAMILY OF DISCRIMINATING MOLECULES FOR NEUTRON AND GAMMA RAYS AND IONIC LIQUIDS CENTRE NAT RECH SCIENT (FR) 2022-02-09 EP disclosed
EP-2976330-A1 NEW FAMILY OF DISCRIMINATING MOLECULES FOR NEUTRON AND GAMMA RAYS AND IONIC LIQUIDS Centre National de la Recherche Scientifique (C.N.R.S.) (FR) 2016-01-27 EP disclosed
WO-2014147078-A1 NEW FAMILY OF DISCRIMINATING MOLECULES FOR NEUTRON AND GAMMA RAYS AND IONIC LIQUIDS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) 2014-09-25 WO disclosed