Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098727 | 1.00 | KDM4E (0.43) | KDM4ECYP1B1ACHEALPLMAPT | |
| SCHEMBL16097485 | 0.89 | KDM4E (0.45) | KDM4EACHEALPLMAPTGAA | |
| SCHEMBL16097484 | 0.89 | KDM4E (0.45) | KDM4EACHEALPLMAPTGAA | |
| SCHEMBL16096362 | 0.88 | KDM4E (0.34) | KDM4EMAPTGAACTHMEN1 | |
| SCHEMBL16096364 | 0.88 | KDM4E (0.34) | KDM4EMAPTGAACTHMEN1 | |
| SCHEMBL17499392 | 0.86 | KDM4E (0.33) | KDM4EGAACTH | |
| SCHEMBL28040282 | 0.85 | KDM4E (0.33) | KDM4EGAACTH | |
| SCHEMBL16096547 | 0.82 | NR4A1 (0.47) | KDM4ECYP1B1ACHEMAPTGAA | |
| SCHEMBL16096549 | 0.82 | NR4A1 (0.47) | KDM4ECYP1B1ACHEMAPTGAA | |
| SCHEMBL16097085 | 0.82 | L3MBTL1 (0.41) | KDM4EMAPTGAACTHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |