Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 5/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939878 | 1.00 | HASPIN (0.59) | HASPINDYRK1AHTR2AHTR2CROCK2 | |
| SCHEMBL16098606 | 0.84 | HASPIN (0.42) | HASPINDYRK1AHTR2AHTR2CROCK2 | |
| SCHEMBL16098607 | 0.83 | HASPIN (0.41) | HASPINDYRK1AROCK2MAOAGSK3B | |
| SCHEMBL23234241 | 0.82 | HASPIN (0.39) | HASPINDYRK1AHTR2AHTR2CROCK2 | |
| SCHEMBL30939921 | 0.82 | HASPIN (0.39) | HASPINDYRK1AHTR2AHTR2CROCK2 | |
| SCHEMBL30939903 | 0.82 | PER2 (0.46) | DYRK1AHTR2AHTR2C | |
| SCHEMBL16103007 | 0.82 | PER2 (0.46) | DYRK1AHTR2AHTR2C | |
| SCHEMBL16099839 | 0.80 | HASPIN (0.39) | HASPINROCK2MAOADYRK2MAOB | |
| SCHEMBL30940009 | 0.80 | DYRK1A (0.69) | HASPINDYRK1AHTR2AHTR2CMAOA | |
| SCHEMBL16123598 | 0.80 | DYRK1A (0.69) | HASPINDYRK1AHTR2AHTR2CMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-B1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOQC INC (CA) | 2021-04-21 | — | — | EP | claimed |
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | claimed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | claimed |
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |