Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CNR2 | P34972 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692026 | 0.88 | ALDH1A1 (0.76) | ALDH1A1HPGDKDM4ECNR2MAPT | |
| SCHEMBL16099245 | 0.87 | ALDH1A1 (0.66) | ALDH1A1HPGDKDM4ECNR2MAPT | |
| SCHEMBL27900931 | 0.83 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ECNR2MAPT | |
| SCHEMBL2774463 | 0.83 | HPGD (0.79) | ALDH1A1HPGDKDM4ECNR2MAPT | |
| SCHEMBL8175739 | 0.83 | CNR2 (0.67) | ALDH1A1HPGDCNR2CNR1NPC1 | |
| SCHEMBL16120022 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ECNR2CNR1 | |
| SCHEMBL27918668 | 0.81 | CNR2 (0.70) | ALDH1A1HPGDCNR2CNR1NPC1 | |
| SCHEMBL5662028 | 0.80 | HPGD (0.72) | ALDH1A1HPGDKDM4EMAPTPOLB | |
| SCHEMBL28050802 | 0.80 | CNR2 (0.77) | ALDH1A1HPGDCNR2CNR1NPC1 | |
| SCHEMBL28389333 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ECNR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | AR, KLK3, BRDT | ALDH1A1 371/4885HPGD 166/4885KDM4E 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.