Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.45 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099021 | 0.95 | HASPIN (0.47) | HASPINNFATC1GSK3BDYRK1AALDH1A1 | |
| SCHEMBL16099658 | 0.85 | NFATC1 (0.43) | NFATC1GSK3BDYRK1ATSHRLMNA | |
| SCHEMBL16093883 | 0.82 | PDE5A (0.37) | NFATC1GSK3BDYRK1AALDH1A1LMNA | |
| SCHEMBL16098852 | 0.81 | HASPIN (0.45) | HASPINNFATC1GSK3BDYRK1AALDH1A1 | |
| SCHEMBL16098887 | 0.80 | HASPIN (0.66) | HASPINDYRK1ATSHRTP53CYP1A2 | |
| SCHEMBL16099514 | 0.80 | DYRK1A (0.49) | HASPINDYRK1AALDH1A1TP53CYP1A2 | |
| SCHEMBL16093943 | 0.80 | NFATC1 (0.47) | NFATC1GSK3BDYRK1ACYP3A4KDM4E | |
| SCHEMBL16093779 | 0.79 | HASPIN (0.71) | HASPINDYRK1ATP53CYP1A2CYP3A4 | |
| SCHEMBL16099752 | 0.78 | HASPIN (0.47) | HASPINDYRK1AALDH1A1TP53CYP1A2 | |
| SCHEMBL16098427 | 0.76 | HASPIN (0.43) | HASPINDYRK1ATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |