Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099514 | 0.89 | DYRK1A (0.49) | HASPINMAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16098887 | 0.82 | HASPIN (0.66) | HASPINMAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16093779 | 0.81 | HASPIN (0.71) | HASPINMAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16099754 | 0.78 | HASPIN (0.45) | HASPINMAOAMAOBCYP1A2TP53 | |
| SCHEMBL16098606 | 0.78 | HASPIN (0.42) | HASPINMAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16100006 | 0.78 | ADORA3 (0.41) | HASPINMAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16099021 | 0.76 | HASPIN (0.47) | HASPINMAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16098427 | 0.76 | HASPIN (0.43) | HASPINMAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16099097 | 0.74 | HASPIN (0.45) | HASPINMAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16098699 | 0.72 | ADORA3 (0.44) | HASPINCYP2D6DYRK1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |