Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.66 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354443 | 0.83 | SYK (0.73) | SYK | |
| SCHEMBL1354438 | 0.83 | SYK (0.73) | SYK | |
| SCHEMBL14977488 | 0.81 | SYK (0.58) | SYKZAP70KCNH2AURKB | |
| SCHEMBL1353731 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL1353737 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL1354470 | 0.79 | SYK (1.00) | SYK | |
| SCHEMBL1354473 | 0.79 | SYK (1.00) | SYK | |
| SCHEMBL12904968 | 0.79 | SYK (0.67) | SYKZAP70KCNH2AURKB | |
| SCHEMBL16202719 | 0.79 | SYK (0.67) | SYKZAP70KCNH2AURKB | |
| SCHEMBL14977578 | 0.78 | SYK (0.64) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152768-A1 | CYCLOHEXANEDIAMINE COMPOUNDS AND METHODS FOR THEIR PREPARATION | PORTOLA PHARMACEUTICALS, INC. (US) | 2014-09-25 | — | — | WO | disclosed |