⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084604 | 0.88 | L3MBTL1 (0.44) | — | |
| SCHEMBL7459149 | 0.82 | — | — | |
| SCHEMBL2659213 | 0.80 | — | — | |
| SCHEMBL23012478 | 0.79 | L3MBTL1 (0.38) | — | |
| SCHEMBL16101416 | 0.78 | IKBKE (0.38) | — | |
| SCHEMBL16100862 | 0.78 | NAMPT (0.44) | — | |
| SCHEMBL12311437 | 0.77 | L3MBTL1 (0.55) | — | |
| SCHEMBL11623307 | 0.77 | — | — | |
| SCHEMBL292775 | 0.76 | — | — | |
| SCHEMBL16101722 | 0.75 | MAP3K5 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035375-A1 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2026-02-05 | — | — | US | disclosed |
| US-12459952-B2 | TREM2 modulators | MUNA THERAPEUTICS APS (DK) | 2025-11-04 | — | — | US | disclosed |
| US-20250223293-A1 | TREM2 MODULATORS | MUNA THERAPEUTICS APS (DK) | 2025-07-10 | — | — | US | disclosed |
| EP-3632898-B1 | EP4 ANTAGONIST | ONO PHARMACEUTICAL CO (JP) | 2023-07-12 | — | — | EP | disclosed |
| US-11479550-B2 | EP4 antagonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-10-25 | — | — | US | disclosed |
| US-20210163466-A1 | EP4 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |
| EP-3632898-A1 | EP4 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |
| US-20180319793-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-11-08 | — | — | US | disclosed |
| US-9994562-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |
| US-20160039808-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC | 2016-02-11 | — | — | US | disclosed |
| EP-2970211-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151106-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |