Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101461 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499736 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2ARAB9ANPC1 | |
| SCHEMBL17499739 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2ARAB9ANPC1 | |
| SCHEMBL17499095 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4EKMT2ARAB9ANPC1 | |
| SCHEMBL16096009 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10KMT2ARAB9A | |
| SCHEMBL17499561 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10KMT2ARAB9A | |
| SCHEMBL16098074 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL16098075 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL16101479 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL16101261 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |