Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685103 | 0.86 | ESR1 (0.74) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL1612744 | 0.84 | ESR1 (0.58) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL21100336 | 0.78 | ESR1 (0.64) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL861221 | 0.76 | ESR1 (0.61) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL394340 | 0.76 | ESR1 (0.61) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL15706822 | 0.76 | ESR1 (0.61) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL1611333 | 0.75 | ESR1 (0.54) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL73405 | 0.74 | ESR1 (1.00) | ESR1THRATHRBSLC6A2SLC6A4 | |
| SCHEMBL19848644 | 0.74 | ESR1 (0.58) | ESR1THRATHRBSLC6A2HTR2A | |
| SCHEMBL5365005 | 0.74 | ESR1 (0.58) | ESR1THRATHRBSLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418071-A2 | New N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase | PFIZER INC. (US) | 1991-03-20 | — | — | EP | claimed |
| US-4623662-A | ANTICHOLESTEROL, ANTILIPEMIC | AMERICAN CYANAMID COMPANY (US) | 1986-11-18 | — | — | US | claimed |
| CN-106459523-B | The manufacturing method of resin combination, cross-linking agent and cross-linking agent | 住友化学株式会社 | 2019-11-19 | — | — | CN | disclosed |
| CN-110352213-A | Film | 住友化学株式会社 | 2019-10-18 | — | — | CN | disclosed |
| CN-106488935-B | Transistion metal compound, transition-metal catalyst composition and Alathon or ethylene and alpha olefin copolymer preparation method | 沙特基础工业爱思开 NEXLENE 私人有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-105566530-B | The method that the copolymer of Alathon or ethylene and alpha-olefin is prepared using transition-metal catalyst composition | 沙特基础工业 爱思开 NEXLENE私人有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-103709297-B | Ethylene-alpha-olefin copolymer | 住友化学株式会社 | 2018-01-09 | — | — | CN | disclosed |
| CN-104628909-B | The method for preparing the copolymer of Alathon or ethene and alhpa olefin | 沙特基础工业 爱思开 NEXLENE私人有限公司 | 2017-09-05 | — | — | CN | disclosed |
| CN-103732632-B | Method for producing olefin block polymer using Group 4 transition metal complex | 住友化学株式会社 | 2017-07-07 | — | — | CN | disclosed |
| CN-103732606-B | New cyclopentano [B] fluorenyl transition metal compound, the carbon monoxide-olefin polymeric comprising it and the method using its copolymer for preparing Alathon or ethene and alhpa olefin | 沙特基础工业爱思开NEXLENE私人有限公司 | 2017-06-09 | — | — | CN | disclosed |
| CN-106715539-A | Modified solid polyalkylaluminoxane and catalyst for olefin oligomerization | 住友化学株式会社 | 2017-05-24 | — | — | CN | disclosed |
| EP-1680189-A2 | COMBINATIONS OF LIPID MODULATING AGENTS AND SUBSTITUTED AZETIDINONES AND TREATMENTS FOR VASCULAR CONDITIONS | SCHERING CORPORATION (US) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005046797-A2 | COMBINATIONS OF LIPID MODULATING AGENTS AND SUBSTITUTED AZETIDINONES AND TREATMENTS FOR VASCULAR CONDITIONS | SCHERING CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |
| CN-1174002-C | Transition metal compound, catalyst for polyaddition and method for preparing addition polymer | 住友化学工业株式会社 | 2004-11-03 | — | — | CN | disclosed |
| CN-1163522-C | Olefine polymerization catalyst and method for production of olefine polymer using it | 住友化学工业株式会社 | 2004-08-25 | — | — | CN | disclosed |
| CN-1330085-A | Transition metal compound, catalyst for polyaddition and method for preparing addition polymer | SUMITOMO CHEMICAL CO (JP) | 2002-01-09 | — | — | CN | disclosed |
| CN-1286271-A | Olefine polymerization catalyst and method for production of olefine polymer using it | SUMITOMO CHEMICAL CO (JP) | 2001-03-07 | — | — | CN | disclosed |
| US-5032616-A | Plants | TRACOR, INC. | 1991-07-16 | — | — | US | disclosed |
| EP-0418071-A2 | New N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase | PFIZER INC. (US) | 1991-03-20 | — | — | EP | disclosed |
| EP-0258853-B1 | 4-SUBSTITUTED CYCLOHEXYLAMINE DERIVATIVES, FUNGICIDES CONTAINING THEM AND PROCESS FOR COMBATING FUNGI | BASF Aktiengesellschaft (DE) | 1990-07-11 | — | — | EP | disclosed |