Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL28043762 | 0.98 | HIF1A (0.48) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| Bromide SCHEMBL28054108 | 0.96 | HIF1A (0.46) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| Iodide SCHEMBL1054412 | 0.95 | HIF1A (0.50) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| Water SCHEMBL3422252 | 0.95 | HIF1A (0.50) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL477383 | 0.95 | HIF1A (0.50) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| Iodide SCHEMBL28057254 | 0.91 | HIF1A (0.46) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| SCHEMBL9180560 | 0.89 | HIF1A (0.44) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| SCHEMBL28131525 | 0.89 | HIF1A (0.44) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| Perchlorate SCHEMBL11848103 | 0.89 | HIF1A (0.44) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 | |
| SCHEMBL8972925 | 0.89 | HIF1A (0.44) | HIF1ACYP2C19TSHRALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 695 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060234-A | Preparation method of self-repairing epoxidized natural rubber composite material based on four-fold hydrogen bond-four sulfur bond cooperation | 上海工程技术大学 | 2026-05-19 | — | — | CN | claimed |
| CN-116199928-B | Surface modified antibacterial polyurethane material, preparation method and application | 江南大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120118320-A | Polyester-based multi-block thermotropic shape memory material with adjustable performance and preparation method thereof | 大连理工大学 | 2025-06-10 | — | — | CN | claimed |
| US-20250136841-A1 | BLENDED FURNISH WITH IMPROVED PERFORMANCE AND METHODS OF MAKING AND USING THE SAME | ARCLIN USA LLC (US) | 2025-05-01 | — | — | US | claimed |
| CN-118791717-A | Polyether ester-based thermoplastic elastomer and preparation method thereof | 大连理工大学 | 2024-10-18 | — | — | CN | claimed |
| WO-2024109000-A1 | LITHIUM BATTERY SEPARATOR AND PREPARATION METHOD THEREFOR | 安徽绿沃循环能源科技有限公司 | 2024-05-30 | — | — | WO | claimed |
| CN-118085283-A | Bismaleimide resin modifier and modified bismaleimide resin | 四川大学 | 2024-05-28 | — | — | CN | claimed |
| CN-117142919-A | Preparation method of 1-phenyl-1, 3-butadiene polar monomer and corresponding polymer thereof | 上海大学 | 2023-12-01 | — | — | CN | claimed |
| WO-2023118045-A1 | PROCESS FOR THE CONTROLLED SYNTHESIS OF VOCLOSPORIN | CURIA SPAIN, S.A.U. (ES) | 2023-06-29 | — | — | WO | claimed |
| EP-4201952-A1 | PROCESS FOR THE CONTROLLED SYNTHESIS OF VOCLOSPORIN | CURIA SPAIN, S.A.U. (ES) | 2023-06-28 | — | — | EP | claimed |
| EP-0389617-B1 | TREATMENT OF RHODIUM CATALYSTS | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1993-03-17 | — | — | EP | claimed |
| EP-0180471-B1 | NOVEL THERMOPLASTIC POLYESTER COMPOSITIONS CONTAINING CERTAIN LOW MOLECULAR WEIGHT DEPOXIDE RESINS AND HAVING IMPROVED IMPACT BEHAVIOUR | CELANESE CORPORATION (US) | 1992-03-04 | — | — | EP | claimed |
| US-5086114-A | Reacting anhydride-containing copolymer with diisocyanate and halogenated phthalic anhydride in the prense of quaternary phosphonium compound | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1992-02-04 | — | — | US | claimed |
| EP-0401589-A2 | Method of producing imide bond-containing resins | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1990-12-12 | — | — | EP | claimed |
| EP-0389617-A1 | TREATMENT OF RHODIUM CATALYSTS. | UNION CARBIDE CHEM PLASTIC (US) | 1990-10-03 | — | — | EP | claimed |
| US-4929767-A | PRETREATING AN ORGANIC SOLUTION OF A DEACTIVATED RHODIUM-PHOSPHINE COMPLEX TO IMPROVE RHODIUM EXTRACTABILITY INTO AN AQUEOUS SOLUTION; REUSE | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-05-29 | — | — | US | claimed |
| US-4880866-A | TRIPHENYLPHOSPHONIUM CATALYSTS BLENDS, BUTADIENE OR BUTADIENE-STYRENE COPOLYMERS | HOECHST CELANESE (US) | 1989-11-14 | — | — | US | claimed |
| EP-0180471-A2 | Novel thermoplastic polyester compositions containing certain low molecular weight depoxide resins and having improved impact behaviour | CELANESE CORPORATION (US) | 1986-05-07 | — | — | EP | claimed |
| US-4101601-A | Epoxy-catalyst additive system to produce higher I.V. polybutylene terephthalate from low I.V. polymer | CELANESE CORPORATION (US) | 1978-07-18 | — | — | US | claimed |
| US-3997705-A | Method of coagulating a fluoro-elastomer from an aqueous dispersion thereof | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-12-14 | — | — | US | claimed |