Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823563 | 0.99 | MAPT (0.31) | MAPTALDH1A1LMNALRRK2GSK3B | |
| SCHEMBL16097071 | 0.91 | MAPT (0.31) | MAPTALDH1A1LMNALRRK2GSK3B | |
| SCHEMBL28039921 | 0.89 | MAPT (0.31) | MAPTALDH1A1LMNALRRK2GSK3B | |
| SCHEMBL16098019 | 0.86 | KMT2A (0.37) | MAPTALDH1A1LMNALRRK2 | |
| SCHEMBL17499227 | 0.85 | MAPT (0.32) | MAPTALDH1A1LMNALRRK2GSK3B | |
| SCHEMBL16101279 | 0.84 | PTGDR2 (0.31) | MAPTALDH1A1 | |
| SCHEMBL17499295 | 0.84 | SMN1; SMN2 (0.34) | MAPTALDH1A1LMNADHX9 | |
| SCHEMBL28039926 | 0.83 | PTGDR2 (0.31) | MAPT | |
| SCHEMBL17499565 | 0.80 | LRRK2 (0.33) | MAPTALDH1A1LMNALRRK2GSK3B | |
| SCHEMBL17499443 | 0.79 | KCNH2 (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |