Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499499 | 0.90 | KCNH2 (0.31) | KCNH2LMNAAPEX1PMP22 | |
| SCHEMBL16098221 | 0.87 | ACHE (0.38) | KCNH2LMNAAPEX1PMP22 | |
| SCHEMBL16098222 | 0.87 | ACHE (0.38) | KCNH2LMNAAPEX1PMP22 | |
| SCHEMBL16096200 | 0.86 | KCNH2 (0.32) | KCNH2LMNAAPEX1PMP22 | |
| SCHEMBL16096199 | 0.86 | KCNH2 (0.32) | KCNH2LMNAAPEX1PMP22 | |
| SCHEMBL17499327 | 0.83 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL16097758 | 0.80 | KCNH2 (0.31) | KCNH2LMNAAPEX1PMP22 | |
| SCHEMBL16097756 | 0.80 | KCNH2 (0.31) | KCNH2LMNAAPEX1PMP22 | |
| SCHEMBL16102431 | 0.79 | MAPT (0.31) | LMNA | |
| SCHEMBL16098373 | 0.79 | MPI (0.38) | KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |