Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 18/20 | 0.61 |
| ▸ | KDM5A | P29375 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095134 | 0.86 | KDM4C (0.60) | KDM4CKDM5AKDM2B | |
| SCHEMBL16095141 | 0.85 | KDM4C (0.61) | KDM4CKDM5AKDM2B | |
| SCHEMBL16033902 | 0.76 | KDM4C (1.00) | KDM4CKDM5AKDM2B | |
| SCHEMBL16102665 | 0.76 | KDM4C (0.68) | KDM4CKDM5ACYP19A1CYP2C9CYP2C19 | |
| SCHEMBL16095046 | 0.72 | KDM4C (0.60) | KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL17604658 | 0.71 | KDM4C (0.43) | KDM4CKDM5AKDM2B | |
| SCHEMBL16095534 | 0.71 | KDM4C (0.62) | KDM4CKDM2B | |
| SCHEMBL17604536 | 0.67 | PHF8 (0.39) | KDM4CKDM5AKDM2B | |
| SCHEMBL17604525 | 0.67 | PHF8 (0.39) | KDM4CKDM5AKDM2B | |
| SCHEMBL17604578 | 0.66 | KDM4C (0.40) | KDM4CKDM5AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |