Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.68 |
| ▸ | KDM5A | P29375 | 2/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | ADH5 | P11766 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095130 | 0.87 | KDM4C (0.69) | KDM4CKDM5AKDM2BKDM5BPHF8 | |
| SCHEMBL16095137 | 0.86 | KDM4C (0.69) | KDM4CKDM5AKDM2B | |
| SCHEMBL16033902 | 0.81 | KDM4C (1.00) | KDM4CKDM5AKDM2BPHF8 | |
| SCHEMBL16102461 | 0.79 | KDM4C (0.42) | KDM4CGCGRPHF8MAPK13MAPK12 | |
| SCHEMBL16102670 | 0.76 | KDM4C (0.61) | KDM4CKDM5AKDM2BCYP19A1CYP2C9 | |
| SCHEMBL16095042 | 0.74 | KDM4C (0.67) | KDM4CKDM5AKDM2BKDM5BPHF8 | |
| SCHEMBL16095526 | 0.72 | KDM4C (0.69) | KDM4CKDM2B | |
| SCHEMBL16034150 | 0.68 | KDM4C (1.00) | KDM4CKDM5AKDM2BPHF8 | |
| SCHEMBL16033749 | 0.68 | KDM4C (1.00) | KDM4CKDM5AKDM2BPHF8 | |
| SCHEMBL16095596 | 0.67 | KDM4C (0.65) | KDM4CKDM5AKDM2BCYP2C9KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |