Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.56 |
| ▸ | RARG | P13631 | 2/20 | 0.56 |
| ▸ | HNF4A | P41235 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014858 | 0.94 | RARB (0.51) | RARBRARGHNF4APTPN11TSHR | |
| SCHEMBL1535879 | 0.94 | RARB (0.62) | RARBRARGHNF4APTPN11TSHR | |
| SCHEMBL19433669 | 0.94 | RARB (0.62) | RARBRARGHNF4APTPN11TSHR | |
| SCHEMBL20026796 | 0.94 | RARB (0.62) | RARBRARGHNF4APTPN11TSHR | |
| SCHEMBL402518 | 0.94 | RARB (0.62) | RARBRARGHNF4APTPN11TSHR | |
| Hydrochloric Acid SCHEMBL2707922 | 0.91 | RARB (0.60) | RARBRARGHNF4APTPN11TSHR | |
| SCHEMBL4367063 | 0.89 | APP (0.52) | RARBRARGHNF4APTPN11TSHR | |
| SCHEMBL17014854 | 0.88 | SLC16A3 (0.54) | RARBRARGHNF4APTPN11TSHR | |
| SCHEMBL15521781 | 0.88 | RARB (0.56) | RARBRARGPTPN11TSHRCYP26A1 | |
| SCHEMBL30872343 | 0.88 | RARB (0.56) | RARBRARGPTPN11TSHRCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841471-B2 | Open metal organic frameworks with exceptional surface area and high gas storage capacity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-23 | — | — | US | disclosed |