Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16103309 | 1.00 | HTR2C (0.41) | HTR2CSLC6A4HTR2AABL1LMNA | |
| SCHEMBL16125925 | 0.90 | HTR2C (0.38) | HTR2CSLC6A4HTR2AABL1LMNA | |
| SCHEMBL19409291 | 0.89 | HTR2C (0.40) | HTR2CSLC6A4HTR2AABL1LMNA | |
| SCHEMBL16102383 | 0.89 | ABL1 (0.36) | HTR2CSLC6A4ABL1LMNAMEN1 | |
| SCHEMBL16125931 | 0.88 | HTR2C (0.36) | HTR2CSLC6A4HTR2AABL1LMNA | |
| SCHEMBL16068284 | 0.88 | HTR2C (0.38) | HTR2CSLC6A4HTR2AABL1LMNA | |
| SCHEMBL16125924 | 0.88 | HTR2C (0.37) | HTR2CSLC6A4HTR2AABL1LMNA | |
| SCHEMBL16068182 | 0.87 | HTR2C (0.37) | HTR2CSLC6A4HTR2AABL1LMNA | |
| SCHEMBL16201299 | 0.85 | HTR2C (0.36) | HTR2CSLC6A4HTR2AABL1LMNA | |
| SCHEMBL16058330 | 0.85 | HTR2C (0.36) | HTR2CSLC6A4HTR2AABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970181-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153208-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |