Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16068284 | 0.93 | HTR2C (0.38) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL16068182 | 0.91 | HTR2C (0.37) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL16201299 | 0.90 | HTR2C (0.36) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL16058330 | 0.90 | HTR2C (0.36) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL16103308 | 0.89 | HTR2C (0.41) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL16103309 | 0.89 | HTR2C (0.41) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL17610254 | 0.89 | HTR2C (0.36) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL17621973 | 0.89 | HTR2C (0.36) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL20393077 | 0.89 | HTR2C (0.36) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 | |
| SCHEMBL16194361 | 0.88 | HTR2C (0.37) | HTR2CSLC6A4HTR2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190077795-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2019-03-14 | — | — | US | disclosed |
| US-20170283400-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077795-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | PRMT1, PRMT3, PRMT5 | HTR2C 4449/4885SLC6A4 2495/4885HTR2A 3980/4885 |
| US-20170283400-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | PRMT1, PRMT3, PRMT5 | HTR2C 4449/4885SLC6A4 2495/4885HTR2A 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.