Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 6/20 | 0.68 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | THRB | P10828 | 7/20 | 0.67 |
| ▸ | BLM | P54132 | 7/20 | 0.67 |
| ▸ | RECQL | P46063 | 6/20 | 0.67 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.67 |
| ▸ | TOP2A | P11388 | 5/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104164 | 0.93 | MEN1 (0.68) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL16900728 | 0.89 | MEN1 (0.82) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL22667675 | 0.89 | MEN1 (0.82) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL10239265 | 0.89 | MEN1 (0.69) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL14703485 | 0.88 | MEN1 (0.73) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL14706187 | 0.88 | MEN1 (0.73) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL18751205 | 0.88 | MEN1 (0.73) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL10455683 | 0.88 | MEN1 (0.68) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL15472836 | 0.88 | MEN1 (0.86) | S100A4PAX8HSP90AA1MEN1KMT2A | |
| SCHEMBL23295088 | 0.86 | S100A4 (0.69) | S100A4PAX8HSP90AA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125026-B1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR THE INHIBITION AND AMELIORATION OF DISEASE | ALLACCEM INC (US) | 2014-09-24 | — | — | EP | disclosed |