Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052692 | 0.95 | MET (0.56) | METNQO2NPY5R | |
| SCHEMBL3057775 | 0.88 | MET (0.66) | METNQO2NPY5R | |
| SCHEMBL13089777 | 0.83 | MET (0.55) | METNQO2 | |
| SCHEMBL3068227 | 0.82 | MET (0.57) | METNQO2 | |
| SCHEMBL3066981 | 0.82 | MET (0.53) | METNQO2NPY5R | |
| Hydrochloric Acid SCHEMBL3052768 | 0.81 | MET (0.56) | METNQO2 | |
| SCHEMBL13089742 | 0.80 | MET (0.60) | METNQO2 | |
| SCHEMBL3065015 | 0.80 | MET (0.65) | METNPY5R | |
| SCHEMBL3070653 | 0.80 | MET (0.59) | METNQO2 | |
| SCHEMBL1950943 | 0.79 | MET (0.84) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049531-B1 | 2-(HETEROCYCLYLBENZYL)PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-09-24 | — | — | EP | disclosed |