Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14144563 | 0.84 | HDAC1 (0.52) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL850268 | 0.83 | MEN1 (0.47) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL16020300 | 0.83 | MMP13 (0.54) | KDM4AL3MBTL1NAMPTGAATSHR | |
| SCHEMBL31431173 | 0.83 | HDAC1 (0.47) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL31019193 | 0.82 | NR1H4 (0.62) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL3897985 | 0.82 | NR1H4 (0.62) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL13691717 | 0.82 | GRM2 (0.47) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL4145619 | 0.82 | KDM4A (0.47) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL21241667 | 0.81 | NSD2 (0.44) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL1829911 | 0.81 | TSHR (0.59) | KDM4AL3MBTL1NAMPTNR1H4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-B9 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2015-10-28 | — | — | EP | disclosed |
| EP-2433940-B1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2014-09-24 | — | — | EP | disclosed |