Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CCR8 | P51685 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105941 | 0.86 | KDM5A (0.47) | FFAR4POLBKDM5AKDM4CKMT2A | |
| SCHEMBL16106013 | 0.85 | FFAR4 (0.36) | MAOBFFAR4POLBMTNR1BKDM5A | |
| SCHEMBL2434798 | 0.78 | FFAR4 (0.44) | MAOBFFAR4KCNH2CCR8KDM5A | |
| SCHEMBL2432717 | 0.77 | FFAR4 (0.45) | MAOBFFAR4KCNH2CCR8KDM5A | |
| SCHEMBL16106041 | 0.70 | GYS1 (0.45) | MAOBFFAR4KDM5AKDM4CKMT2A | |
| Bicarbonate SCHEMBL14796813 | 0.69 | KDM5A (0.48) | FFAR4POLBKDM5AKDM4CKMT2A | |
| SCHEMBL2432324 | 0.69 | MAOB (0.42) | MAOBFFAR4ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2431970 | 0.68 | FFAR1 (0.47) | MAOBFFAR4KCNH2CCR8 | |
| SCHEMBL2433607 | 0.67 | FFAR4 (0.52) | FFAR4 | |
| SCHEMBL14961222 | 0.67 | CCR8 (0.41) | MAOBKCNH2CCR8MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582674-B1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | CYMABAY THERAPEUTICS INC (US) | 2014-10-01 | — | — | EP | claimed |