Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393540 | 0.86 | MAPT (0.49) | KDM4EBRD4LMNAHSP90AA1MAPT | |
| SCHEMBL16106633 | 0.84 | OPRK1 (0.54) | KDM4ELMNAMAPTOPRK1KMT2A | |
| SCHEMBL16106459 | 0.81 | MAPT (0.51) | KDM4ELMNAHSP90AA1MAPTOPRK1 | |
| SCHEMBL28250159 | 0.81 | CCR1 (0.48) | KDM4EBRD4LMNAHSP90AA1MAPT | |
| SCHEMBL16106430 | 0.81 | PDE4B (0.42) | KDM4ENQO2 | |
| SCHEMBL16106477 | 0.81 | PDE4B (0.42) | KDM4ENQO2 | |
| SCHEMBL16106657 | 0.81 | PDE4B (0.42) | KDM4ENQO2 | |
| SCHEMBL16106428 | 0.81 | PDE4B (0.42) | KDM4ENQO2 | |
| SCHEMBL16106568 | 0.81 | PDE4B (0.42) | KDM4ENQO2 | |
| SCHEMBL16106630 | 0.81 | PDE4B (0.42) | KDM4ENQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9302992-B2 | Multifunctional quinoline derivatives as anti-neurodegenerative agents | Annji Pharmaceutical Co., Ltd. (TW) | 2016-04-05 | — | — | US | claimed |
| US-20140296251-A1 | MULTIFUNCTIONAL QUINOLINE DERIVATIVES AS ANTI-NEURODEGENERATIVE AGENTS | Annji Pharmaceutical Co., Ltd. (TW) | 2014-10-02 | — | — | US | claimed |
| US-9302992-B2 | Multifunctional quinoline derivatives as anti-neurodegenerative agents | Annji Pharmaceutical Co., Ltd. (TW) | 2016-04-05 | — | — | US | disclosed |
| US-9302992-B2 | Multifunctional quinoline derivatives as anti-neurodegenerative agents | Annji Pharmaceutical Co., Ltd. (TW) | 2016-04-05 | — | — | US | disclosed |
| US-9302992-B2 | Multifunctional quinoline derivatives as anti-neurodegenerative agents | Annji Pharmaceutical Co., Ltd. (TW) | 2016-04-05 | — | — | US | disclosed |
| US-20140296251-A1 | MULTIFUNCTIONAL QUINOLINE DERIVATIVES AS ANTI-NEURODEGENERATIVE AGENTS | Annji Pharmaceutical Co., Ltd. (TW) | 2014-10-02 | — | — | US | disclosed |
| US-20140296251-A1 | MULTIFUNCTIONAL QUINOLINE DERIVATIVES AS ANTI-NEURODEGENERATIVE AGENTS | Annji Pharmaceutical Co., Ltd. (TW) | 2014-10-02 | — | — | US | disclosed |
| US-20140296251-A1 | MULTIFUNCTIONAL QUINOLINE DERIVATIVES AS ANTI-NEURODEGENERATIVE AGENTS | Annji Pharmaceutical Co., Ltd. (TW) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296251-A1 | MULTIFUNCTIONAL QUINOLINE DERIVATIVES AS ANTI-NEURODEGENERATIVE AGENTS | NLN, SNCA, CLN6 | KDM4E 3330/4885BRD4 496/4885LMNA 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.