Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 15/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1609867 | 0.93 | PDE10A (0.39) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1609158 | 0.89 | PDE10A (0.39) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1610413 | 0.88 | PDE10A (0.38) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL12713482 | 0.85 | SYK (0.36) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1609916 | 0.82 | PDE10A (0.37) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1609868 | 0.82 | PDE10A (0.35) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL13769181 | 0.81 | PDE10A (0.40) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL721836 | 0.77 | PDE10A (0.53) | PDE10ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL718535 | 0.72 | TSHR (0.41) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL13769259 | 0.69 | TSHR (0.42) | PDE10ANR1I2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE10A 1704/4885CHRM3 2705/4885PDE4A 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.