SCHEMBL16110262

SCHEMBL16110262

CCC1(c2ccc(C)cc2)OC1C(=O)OC1CCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA1 P02708 1/20 0.37
CHRNG P07510 1/20 0.37
ITGA5 P08648 1/20 0.37
CHRNB1 P11230 1/20 0.37
CHRNB2 P17787 1/20 0.37
SLC6A2 P23975 1/20 0.37
CHRNB4 P30926 1/20 0.37
SLC6A4 P31645 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
SLC6A3 Q01959 1/20 0.37
CHRND Q07001 1/20 0.37
FABP7 O15540 1/20 0.36
FABP5 Q01469 1/20 0.36
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
CHRM2 P08172 3/20 0.34
CHRM4 P08173 3/20 0.34
CHRM5 P08912 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967527 0.99 FABP7 (0.38) CHRNA1CHRNGITGA5CHRNB1CHRNB2
SCHEMBL16108665 0.97 CHRNA1 (0.39) CHRNA1CHRNGITGA5CHRNB1CHRNB2
SCHEMBL16109685 0.95 SCN1A (0.36) CHRNA1CHRNGITGA5CHRNB1CHRNB2
SCHEMBL14967696 0.88 FABP7 (0.45) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL16109861 0.88 EPHX2 (0.39) SLC6A4SLC6A3CHRM2CHRM4CHRM5
SCHEMBL14967344 0.87 FABP7 (0.47) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL16110551 0.86 EPHX2 (0.41) SLC6A4SLC6A3FABP7FABP5CHRM2
SCHEMBL14967083 0.86 FABP7 (0.42) FABP7FABP5CHRM2CHRM4CHRM5
SCHEMBL16109610 0.85 SLC6A4 (0.40) SLC6A2SLC6A4SLC6A3CHRM2CHRM1
SCHEMBL14967321 0.83 FABP7 (0.38) FABP7FABP5CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed