SCHEMBL14967321

SCHEMBL14967321

CCC1(c2ccccc2)OC1C(=O)OC1CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.38
FABP5 Q01469 1/20 0.38
CHRM3 P20309 3/20 0.37
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
HCAR3 P49019 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.36
HTT P42858 2/20 0.35
TSHR P16473 1/20 0.35
OPRM1 P35372 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967083 0.95 FABP7 (0.42) FABP7FABP5CHRM3CHRM2CHRM4
SCHEMBL14967696 0.95 FABP7 (0.45) FABP7FABP5CHRM3CHRM2CHRM4
SCHEMBL14967344 0.93 FABP7 (0.47) FABP7FABP5CHRM3CHRM2CHRM4
SCHEMBL16109685 0.88 SCN1A (0.36) MEN1KMT2AOPRM1ALDH1A1
SCHEMBL14967654 0.85 ATM (0.40) MEN1KMT2AGAAHTTTSHR
SCHEMBL14967939 0.84 TSHR (0.48) HCAR3HCAR2MEN1CYP1A2CYP2D6
SCHEMBL16110262 0.83 CHRNA1 (0.37) FABP7FABP5CHRM3CHRM2CHRM4
SCHEMBL16108665 0.83 CHRNA1 (0.39) FABP7FABP5CHRM3CHRM2CHRM4
SCHEMBL9692301 0.82 HTT (0.45) HCAR3HCAR2MEN1CYP2D6CYP2C19
SCHEMBL14967527 0.82 FABP7 (0.38) FABP7FABP5CHRM3CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed