Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111321 | 1.00 | F2 (0.51) | F2F10ALDH1A1MAPTRAB9A | |
| SCHEMBL17451530 | 1.00 | F2 (0.51) | F2F10ALDH1A1MAPTRAB9A | |
| SCHEMBL17451506 | 0.95 | F2 (0.47) | F2F10ALDH1A1MAPTRAB9A | |
| SCHEMBL17451477 | 0.75 | KMT2A (0.53) | MAPTRAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL11504407 | 0.75 | CYP1A2 (0.65) | MAPTRAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL11504406 | 0.75 | CYP1A2 (0.65) | MAPTRAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL9717141 | 0.73 | CA1 (0.66) | ALDH1A1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL10618582 | 0.73 | CA1 (0.66) | ALDH1A1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL11616195 | 0.73 | CA1 (0.66) | ALDH1A1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL9717146 | 0.73 | CA1 (0.66) | ALDH1A1MAPTRAB9AKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208012-B2 | Compounds for treating inflammatory and hyperproliferative diseases | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-02-19 | — | — | US | disclosed |
| US-20160016931-A1 | COMPOUNDS FOR TREATING INFLAMMATORY AND HYPERPROLIFERATIVE DISEASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2016-01-21 | — | — | US | disclosed |
| WO-2014160339-A1 | COMPOUNDS FOR TREATING INFLAMMATORY AND HYPERPROLIFERATIVE DISEASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208012-B2 | Compounds for treating inflammatory and hyperproliferative diseases | NFKBIA, PCNA, MYC | F2 3103/4885F10 3849/4885ALDH1A1 1609/4885 |
| US-20160016931-A1 | COMPOUNDS FOR TREATING INFLAMMATORY AND HYPERPROLIFERATIVE DISEASES | NFKBIA, PCNA, MYC | F2 3103/4885F10 3849/4885ALDH1A1 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.