Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | MYC | P01106 | 2/20 | 0.43 |
| ▸ | MAX | P61244 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504407 | 0.89 | CYP1A2 (0.65) | KMT2AMEN1CYP1A2PIM1PIM2 | |
| SCHEMBL11504406 | 0.89 | CYP1A2 (0.65) | KMT2AMEN1CYP1A2PIM1PIM2 | |
| SCHEMBL17451506 | 0.83 | F2 (0.47) | KMT2AMEN1CYP1A2PIM1PIM2 | |
| SCHEMBL17451495 | 0.81 | KMT2A (0.56) | KMT2AMEN1CYP1A2PIM1PIM2 | |
| SCHEMBL17451530 | 0.75 | F2 (0.51) | KMT2AMEN1CYP1A2NPC1RAB9A | |
| SCHEMBL16111321 | 0.75 | F2 (0.51) | KMT2AMEN1CYP1A2NPC1RAB9A | |
| SCHEMBL16111320 | 0.75 | F2 (0.51) | KMT2AMEN1CYP1A2NPC1RAB9A | |
| SCHEMBL15561380 | 0.75 | ACHE (0.48) | KMT2AMEN1CYP1A2ACHECARM1 | |
| SCHEMBL16755587 | 0.75 | ACHE (0.48) | KMT2AMEN1CYP1A2ACHECARM1 | |
| SCHEMBL19840306 | 0.75 | ACHE (0.48) | KMT2AMEN1CYP1A2ACHECARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160016931-A1 | COMPOUNDS FOR TREATING INFLAMMATORY AND HYPERPROLIFERATIVE DISEASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016931-A1 | COMPOUNDS FOR TREATING INFLAMMATORY AND HYPERPROLIFERATIVE DISEASES | NFKBIA, PCNA, MYC | KMT2A 3236/4885MEN1 885/4885CYP1A2 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.