Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051465 | 0.82 | PBRM1 (0.35) | PBRM1NR1H2NR1H3DCUN1D1IDO1 | |
| SCHEMBL31473932 | 0.79 | BRD4 (0.38) | PBRM1NR1H2NR1H3DCUN1D1ALDH1A1 | |
| SCHEMBL2099637 | 0.78 | IDO1 (0.48) | IDO1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL1395368 | 0.76 | IDO1 (0.48) | DCUN1D1IDO1MAPK1ALDH1A1MAPT | |
| SCHEMBL10801976 | 0.76 | DCUN1D1 (0.43) | DCUN1D1IDO1MAPK1ALDH1A1MAPT | |
| SCHEMBL1528053 | 0.76 | LDHA (0.52) | NR1H2NR1H3DCUN1D1IDO1MAPK1 | |
| SCHEMBL11686059 | 0.76 | IDO1 (0.52) | DCUN1D1IDO1ALDH1A1MAPTHPGD | |
| SCHEMBL9173243 | 0.76 | IDO1 (0.47) | IDO1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL15125436 | 0.76 | GAA (0.52) | DCUN1D1IDO1MAPK1ALDH1A1HPGD | |
| SCHEMBL28057480 | 0.76 | DCUN1D1 (0.43) | NR1H2NR1H3DCUN1D1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174865-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016018875-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-02-04 | — | — | WO | disclosed |
| EP-2970176-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014160031-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-10-02 | — | — | WO | disclosed |