Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713527 | 0.84 | EPHX1 (1.00) | EPHX1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL11171600 | 0.82 | EPHX1 (0.68) | EPHX1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL8612464 | 0.82 | EPHX1 (0.77) | EPHX1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL16119713 | 0.82 | EPHX1 (0.72) | EPHX1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL9686610 | 0.81 | EPHX1 (0.76) | EPHX1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL31389407 | 0.81 | EPHX1 (0.76) | EPHX1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL16030042 | 0.80 | ALDH1A1 (0.62) | EPHX1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6118209 | 0.80 | EPHX1 (0.78) | EPHX1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL11171176 | 0.80 | EPHX1 (0.78) | EPHX1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL14577329 | 0.79 | EPHX1 (0.72) | EPHX1NPC1RAB9ANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970176-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014160031-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-10-02 | — | — | WO | disclosed |