Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 20/20 | 0.69 |
| ▸ | CDK9 | P50750 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16048679 | 0.89 | CCNT1 (0.77) | CCNT1CDK9 | |
| SCHEMBL16039958 | 0.88 | CCNT1 (0.88) | CCNT1CDK9 | |
| SCHEMBL16052141 | 0.88 | CDK9 (0.85) | CCNT1CDK9 | |
| SCHEMBL16051391 | 0.88 | CDK9 (0.85) | CCNT1CDK9 | |
| SCHEMBL16049170 | 0.86 | CCNT1 (0.78) | CCNT1CDK9 | |
| SCHEMBL16048469 | 0.86 | CCNT1 (0.78) | CCNT1CDK9 | |
| SCHEMBL16048657 | 0.86 | CCNT1 (0.66) | CCNT1CDK9 | |
| SCHEMBL16048738 | 0.86 | CDK9 (0.80) | CCNT1CDK9 | |
| SCHEMBL16051230 | 0.84 | CCNT1 (0.86) | CCNT1CDK9 | |
| SCHEMBL16048472 | 0.84 | CCNT1 (0.77) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346813-B2 | Substituted pyrrolo[2,3-d]pyrimindines as CDK9 kinase inhibitors | ABBVIE INC. (US) | 2016-05-24 | — | — | US | claimed |
| EP-2970299-A1 | PYRROLOPYRIMINDINE CDK9 KINASE INHIBITORS | Abbvie Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014160028-A1 | PYRROLOPYRIMINDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-10-02 | — | — | WO | claimed |
| US-9346813-B2 | Substituted pyrrolo[2,3-d]pyrimindines as CDK9 kinase inhibitors | ABBVIE INC. (US) | 2016-05-24 | — | — | US | disclosed |
| EP-2970299-A1 | PYRROLOPYRIMINDINE CDK9 KINASE INHIBITORS | Abbvie Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014160028-A1 | PYRROLOPYRIMINDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-10-02 | — | — | WO | disclosed |