Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476831 | 0.89 | OPRL1 (0.65) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL17799025 | 0.88 | OPRL1 (0.55) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL6543403 | 0.87 | POLB (0.66) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL31567275 | 0.87 | OPRL1 (0.51) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL31223134 | 0.85 | OPRL1 (0.53) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL3897579 | 0.84 | CYP2D6 (0.53) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL3902216 | 0.84 | CCR3 (0.51) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL2702173 | 0.82 | SLC6A3 (0.54) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL3408512 | 0.82 | CYP3A4 (0.54) | OPRL1MEN1KMT2ACYP3A4HSD17B10 | |
| SCHEMBL6110923 | 0.82 | OPRL1 (0.79) | OPRL1MEN1KMT2APOLBCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115943144-B | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-115943144-A | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114075175-A | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2022-02-22 | — | — | CN | disclosed |
| EP-2970200-A1 | PYRIDINE CDK9 KINASE INHIBITORS | Abbvie Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014160017-A1 | PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-10-02 | — | — | WO | disclosed |