SCHEMBL1611328

SCHEMBL1611328

Cc1ccc2c(c1)c(=O)c1cc(C)ccc1n2-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ATM Q13315 1/20 0.48
KMT2A Q03164 4/20 0.48
LMNA P02545 3/20 0.48
MARK4 Q96L34 2/20 0.46
NPC1 O15118 2/20 0.45
MEN1 O00255 2/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.45
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
GFER P55789 1/20 0.44
HPGD P15428 3/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPK1 P28482 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13833031 0.95 KDM4E (0.53) KDM4EL3MBTL1ATMKMT2ALMNA
SCHEMBL679015 0.89 KDM4E (0.56) KDM4EL3MBTL1ATMKMT2ALMNA
SCHEMBL13911848 0.87 KMT2A (0.41) KDM4EL3MBTL1ATMKMT2ALMNA
SCHEMBL25752358 0.86 MAT2A (0.44) KDM4EL3MBTL1ATMKMT2ALMNA
SCHEMBL12433687 0.86 MAT2A (0.47) KDM4EL3MBTL1ATMKMT2AMARK4
SCHEMBL6940379 0.85 KDM4E (0.52) KDM4EL3MBTL1ATMKMT2ALMNA
SCHEMBL21666906 0.84 POLB (0.42) KDM4EKMT2ALMNAMARK4NPC1
SCHEMBL21515583 0.84 KDM4E (0.50) KDM4EL3MBTL1ATMKMT2ALMNA
SCHEMBL17617920 0.84 KDM4E (0.50) KDM4EL3MBTL1ATMKMT2ALMNA
SCHEMBL21515581 0.84 KDM4E (0.50) KDM4EL3MBTL1ATMKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9090819-B2 Organic electroluminescent element, display device, illuminating device and condensed polycyclic heterocyclic compound Konica Minolta, Inc. (JP) 2015-07-28 US disclosed
US-9090819-B2 Organic electroluminescent element, display device, illuminating device and condensed polycyclic heterocyclic compound Konica Minolta, Inc. (JP) 2015-07-28 US disclosed
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2012-04-12 US disclosed
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2012-04-12 US disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND CCNE2, C1S, SCO2 KDM4E 2552/4885L3MBTL1 764/4885ATM 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.