⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818144 | 0.80 | KCNH3 (0.38) | — | |
| SCHEMBL4493350 | 0.79 | KCNH3 (0.33) | — | |
| SCHEMBL1927524 | 0.76 | — | — | |
| SCHEMBL2738310 | 0.76 | — | — | |
| SCHEMBL3388384 | 0.76 | — | — | |
| SCHEMBL24996046 | 0.76 | — | — | |
| SCHEMBL12722834 | 0.76 | — | — | |
| SCHEMBL10907196 | 0.76 | — | — | |
| SCHEMBL7341954 | 0.76 | — | — | |
| SCHEMBL2514383 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016050567-A1 | INSECTICIDAL CYANOTROPANE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-07 | — | — | WO | disclosed |
| US-20160050930-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA LIMITED (UK) | 2016-02-25 | — | — | US | disclosed |
| US-20160046620-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA LIMITED (GB) | 2016-02-18 | — | — | US | disclosed |
| EP-2978318-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | Syngenta Participations AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978316-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | Syngenta Participations AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014154487-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154488-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| CN-103980234-A | Preparation method for intermediate 3-isopropylfuranone derivatives of blood-pressure-reducing medicine aliskiren | CHENGDU ORGANIC CHEMICALS CO | 2014-08-13 | — | — | CN | disclosed |