Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13253702 | 1.00 | ALDH1A1 (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL20715180 | 1.00 | ALDH1A1 (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL47305 | 1.00 | ALDH1A1 (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL8444553 | 1.00 | ALDH1A1 (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL728783 | 1.00 | ALDH1A1 (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL13618315 | 1.00 | ALDH1A1 (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL6383420 | 1.00 | ALDH1A1 (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL20715354 | 0.98 | MAPT (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL21500482 | 0.98 | MAPT (0.32) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL20715355 | 0.98 | MAPT (0.32) | ALDH1A1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014151367-A1 | 1,2,5-SUBSTITUTED BENZIMIDAZOLES AS FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-25 | — | — | WO | disclosed |