Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | LAP3 | P28838 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901567 | 0.92 | LTA4H (0.61) | LTA4HLAP3MMP9MMP8PPARG | |
| SCHEMBL2059140 | 0.88 | TACR1 (0.58) | ACEMAPTS1PR1TACR1 | |
| SCHEMBL13108402 | 0.88 | TACR1 (0.58) | ACEMAPTS1PR1TACR1 | |
| SCHEMBL19465106 | 0.88 | GAA (0.56) | GAARAB9ALTA4HLAP3MMP9 | |
| SCHEMBL16063577 | 0.87 | ATM (0.53) | RAB9ALTA4HPPARGPPARATACR1 | |
| SCHEMBL12869907 | 0.85 | TACR1 (0.53) | MMEACEMAPTS1PR1TACR1 | |
| SCHEMBL10241678 | 0.85 | TACR1 (0.53) | MMEACEMAPTS1PR1TACR1 | |
| SCHEMBL19426879 | 0.85 | TSHR (0.48) | RAB9ALTA4HLAP3MMP9MMP8 | |
| SCHEMBL3499760 | 0.84 | LTA4H (0.65) | GAARAB9ALTA4HLAP3MMP9 | |
| SCHEMBL3499757 | 0.84 | LTA4H (0.65) | GAARAB9ALTA4HLAP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017044584-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | On Target Laboratories, LLC (US) | 2017-03-16 | — | — | WO | disclosed |
| WO-2014149073-A1 | METHODS OF MANUFACTURE AND SYNTHESIS OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR TARGETED IMAGING OF TUMORS | ON TARGET LABORATORIES LLC (US) | 2014-09-25 | — | — | WO | disclosed |