SCHEMBL1611792

SCHEMBL1611792

[C-]#[N+]c1c(C)nn(-c2ccccn2)c1N=Nc1c(C)nn(-c2nc(O)nc(-n3nc(C)c(N=Nc4c(C#N)c(C)nn4-c4ccccn4)c3N)n2)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.42
RAB9A P51151 7/20 0.37
SMN1; SMN2 Q16637 6/20 0.37
NPC1 O15118 6/20 0.37
TDP1 Q9NUW8 4/20 0.37
MAPK1 P28482 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
HPGD P15428 5/20 0.37
ALDH1A1 P00352 4/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
HTT P42858 2/20 0.36
ALOX12 P18054 1/20 0.36
KDM4E B2RXH2 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TP53 P04637 1/20 0.35
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10194298 0.90 MAPT (0.46) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194372 0.89 MAPT (0.43) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194310 0.87 MAPT (0.40) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194317 0.85 MAPT (0.42) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL824562 0.83 MAPT (0.59) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL1612363 0.82 MAPT (0.38) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10052073 0.81 NPC1 (0.35) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194314 0.80 MAPT (0.40) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL824624 0.80 MAPT (0.55) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194376 0.79 MAPT (0.35) MAPTRAB9ASMN1; SMN2NPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808440-B2 Ink composition, ink for inkjet recording and inkjet recording method FUJIFILM CORPORATION (JP) 2014-08-19 US disclosed
US-8399664-B2 Coloring matter, ink, ink for ink jet, ink jet recording method, color toner, and color filter FUJIFILM CORPORATION (JP) 2013-03-19 US disclosed
US-8357235-B2 Inkjet ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-22 US disclosed
US-8262789-B2 Coloring matter, ink, ink for ink jet, ink jet recording method, color toner, and color filter FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-20120095194-A1 COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20120095195-A1 COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20120088910-A1 COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-04-12 US disclosed
US-8114208-B2 Ink jet ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2012-02-14 US disclosed
US-8101011-B2 Mono- and diazo dyes including pyrazol-5-yl rings attached to the azo group; good shades (hues) in the primary colors; colorfastness; photostability; weatherproofing; heat resistance; waterproofing; oxidation/ozone resistance; chemical resistance; storage stability; printing;electrography; displays FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-8083341-B2 Thermal ink-jet ink and ink cartridge using the ink CANON KABUSHIKI KAISHA (JP) 2011-12-27 US disclosed
US-20100071588-A1 INKJET RECORDING YELLOW INK, INKJET RECORDING INK SET AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20090274839-A1 INK JET INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-11-05 US disclosed
US-20090246378-A1 Ink composition, ink set, and image recording method FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-7566362-B2 Ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-07-28 US disclosed
US-7553358-B2 Ink jet ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-06-30 US disclosed
US-20090047430-A1 INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-02-19 US disclosed
US-20080274285-A1 INK JET INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-11-06 US disclosed
US-20080274283-A1 Coloring Matter, Ink, Ink, for Ink Jet, Ink Jet Recording Method, Color Toner, and Color Filter FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080151028-A1 THERMAL INK-JET INK AND INK CARTRIDGE USING THE INK CANON KABUSHIKI KAISHA (JP) 2008-06-26 US disclosed
US-20070109376-A1 Ink composition, ink set and recording method FUJIFILM CORPORATION 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088910-A1 COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER H1-5, IK, H1-2 MAPT 1984/4885RAB9A 487/4885SMN1; SMN2 2316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.