SCHEMBL10194372

SCHEMBL10194372

[C-]#[N+]c1c(C)nn(-c2ccccn2)c1N=Nc1c(C)nn(-c2ccnc(-n3nc(C)c(N=Nc4c(C#N)c(C)nn4-c4ccccn4)c3N)n2)c1N

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.43
RAB9A P51151 7/20 0.36
SMN1; SMN2 Q16637 6/20 0.36
NPC1 O15118 6/20 0.36
TDP1 Q9NUW8 4/20 0.36
MAPK1 P28482 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 4/20 0.36
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
HTT P42858 2/20 0.35
KDM4E B2RXH2 2/20 0.35
TP53 P04637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALOX12 P18054 1/20 0.34
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10194377 0.90 MAPT (0.36) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL1611792 0.89 MAPT (0.42) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194310 0.85 MAPT (0.40) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL824562 0.84 MAPT (0.59) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194317 0.84 MAPT (0.42) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194376 0.82 MAPT (0.35) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL824624 0.81 MAPT (0.55) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10194298 0.79 MAPT (0.46) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL824622 0.77 MAPT (0.53) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL824601 0.75 MAPT (0.53) MAPTRAB9ASMN1; SMN2NPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8118885-B2 Azo pigments, process for producing the azo pigments, and pigment dispersion, coloring composition and ink for inkjet recording containing the pigment FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-20110030583-A1 AZO PIGMENTS, PROCESS FOR PRODUCING THE AZO PIGMENTS, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK FOR INKJET RECORDING CONTAINING THE PIGMENT FUJIFILM COPORATION (JP) 2011-02-10 US disclosed