Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 9/20 | 0.65 |
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 5/20 | 0.48 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | NNMT | P40261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18571721 | 0.91 | PI4KA (0.66) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18297471 | 0.87 | ADK (0.65) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18297604 | 0.83 | ADK (0.62) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16120801 | 0.82 | ADK (0.48) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24293844 | 0.82 | ADK (0.52) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29478311 | 0.82 | ADK (0.52) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16128942 | 0.79 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL20152361 | 0.79 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL19711603 | 0.79 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9940772 | 0.79 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152261-A1 | SUBSTITUTED 7-DEAZAPURINE COMPOUNDS | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |