Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 10/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL946408 | 1.00 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL6130786 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL29187308 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL9495865 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL18526893 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL16872747 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL9694626 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL2985938 | 0.95 | CA2 (0.80) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL21064783 | 0.95 | CA2 (0.90) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 26434 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319591-B1 | AN ELASTOMERIC ARTICLE | MATANG MFG SDN BHD (MY) | 2026-05-27 | — | — | EP | claimed |
| US-20260139175-A1 | USE OF AN AQUEOUS DEICING/ANTI-ICING COMPOSITION FOR REDUCING CARBON FIBRE DEGRADATION | PERSTORP AB (SE) | 2026-05-21 | — | — | US | claimed |
| US-12629377-B2 | Lamotrigine oral liquid suspension and use thereof | ROWP IP HOLDING II LLC | 2026-05-19 | — | — | US | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| EP-4739278-A1 | ANIMAL TREAT FOR ANIMAL ORAL HYGIENE | Dentalis Animal Health Inc. (CA) | 2026-05-13 | — | — | EP | claimed |
| CN-122010709-A | Preparation method and application of fluorine-containing aryl ketone compound | 浙江理工大学 | 2026-05-12 | — | — | CN | claimed |
| US-12624320-B2 | Dissolvable cleaning products free of plastics and/or polyvinyl alcohol | TRU EARTH ENVIRONMENTAL PRODUCTS INC. (CA) | 2026-05-12 | — | — | US | claimed |
| EP-4734961-A1 | NEW METHOD OF PRODUCING AN AQUEOUS MESOPARTICLE COMPOSITION COMPRISING A LIPOPHILIC COMPOUND | BIOGNTX R&D B.V. (NL) | 2026-05-06 | — | — | EP | claimed |
| WO-2026090627-A1 | STABLE PITOLISANT LIQUID FORMULATIONS AND METHOD OF ITS USE | PATEL SANDIPKUMAR (US) | 2026-04-30 | — | — | WO | claimed |
| WO-2026088186-A1 | FERMENTED AND DEHYDRATED ALOE GEL PRODUCT AND PROCESS FOR THE PREPARATION THEREOF | YOSHAY IDO MOSHE (IL) | 2026-04-30 | — | — | WO | claimed |
| US-4099018-A | REACTION WITH CARBOXY COMPOUND, CATALYTIC LEAD COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1978-07-04 | — | — | US | claimed |
| US-4095030-A | CARBOXYLIC ACID SALTS, DILUENTS | PHILLIPS PETROLEUM COMPANY (US) | 1978-06-13 | — | — | US | claimed |
| US-4095037-A | BISMUTH COMPOUNDS, ALKALI METAL COMPOUNDS, NITRATES | PHILLIPS PETROLEUM COMPANY (US) | 1978-06-13 | — | — | US | claimed |
| US-4093815-A | REACTION WITH CARBOXYLIC ACID AND A CARBOXYLIC ACID ANHYDRIDE IN THE PRESENCE OF OXYGEN | PHILLIPS PETROLEUM COMPANY (US) | 1978-06-06 | — | — | US | claimed |
| US-4089755-A | CATIONIC QUATERNARY AMMONIUM SURFACTANT | THE RICHARDSON COMPANY (US) | 1978-05-16 | — | — | US | claimed |
| US-4066390-A | BUILDERS, BUFFERS AND DETERGENTS FOR TEXTILES | DIAMOND SHAMROCK CHEMICALS COMPANY | 1978-01-03 | — | — | US | claimed |
| US-4044041-A | CARBOXYLIC ACID WITH CONJUGATED DIENE | PHILLIPS PETROLEUM COMPANY (US) | 1977-08-23 | — | — | US | claimed |
| US-3964255-A | Method of inflating an automobile passenger restraint bag | SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) | 1976-06-22 | — | — | US | claimed |
| US-3962189-A | PROCESS AND CATALYST-INHIBITOR SYSTEMS FOR PREPARING SYNTHETIC LINEAR POLYESTERS | EASTMAN KODAK COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| US-3952052-A | Process for producing alkali metal salts of aromatic polycarboxylic acids | PHILLIPS PETROLEUM COMPANY (US) | 1976-04-20 | — | — | US | claimed |