Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112171 | 0.96 | MEN1 (0.47) | SLC29A1HDAC6ADORA2AFGFR1FGFR4 | |
| SCHEMBL12112160 | 0.91 | PDE10A (0.48) | SLC29A1HDAC6ADORA2AFGFR1FGFR4 | |
| SCHEMBL13394123 | 0.89 | HDAC6 (0.43) | HDAC6ADORA2AFGFR1FGFR4PI4KA | |
| SCHEMBL13394148 | 0.89 | SLC29A1 (0.47) | SLC29A1HDAC6ADORA2AFGFR1FGFR4 | |
| SCHEMBL15214749 | 0.89 | ADORA2A (0.47) | SLC29A1HDAC6ADORA2AFGFR1FGFR4 | |
| SCHEMBL13394054 | 0.89 | SLC29A1 (0.47) | SLC29A1HDAC6ADORA2AFGFR1FGFR4 | |
| SCHEMBL15214751 | 0.89 | PDE10A (0.51) | SLC29A1HDAC6ADORA2AFGFR1FGFR4 | |
| SCHEMBL15214750 | 0.89 | ADORA2A (0.41) | SLC29A1HDAC6ADORA2AFGFR1FGFR4 | |
| SCHEMBL13394062 | 0.87 | PDE10A (0.52) | SLC29A1ADORA2AFGFR1FGFR4PI4KA | |
| SCHEMBL15214762 | 0.86 | FGFR1 (0.47) | HDAC6FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014149084-A2 | DDX3 AS A BIOMARKER FOR CANCER AND METHODS RELATED THERETO | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-09-25 | — | — | WO | disclosed |