SCHEMBL16123793

SCHEMBL16123793

Cc1cc(OCCCC=O)cc(C)c1-c1cccc(COc2ccc3c(c2)OCC3CC(=O)O)c1

nearest known ligand 0.82

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.82
GNA15 P30679 1/20 0.80
SLC10A1 Q14973 1/20 0.80
ABCC2 Q92887 1/20 0.80
SLCO1B3 Q9NPD5 1/20 0.80
SLCO1B1 Q9Y6L6 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1633142 0.91 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL1634631 0.90 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL21148113 0.89 FFAR1 (0.81) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL1635024 0.89 FFAR1 (0.98) FFAR1GNA15SLC10A1ABCC2SLCO1B3
SCHEMBL16123746 0.89 FFAR1 (0.80) FFAR1GNA15SLC10A1ABCC2SLCO1B3
Fasiglifam SCHEMBL31192643 0.89 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
Fasiglifam SCHEMBL16448793 0.89 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
Fasiglifam SCHEMBL16448782 0.89 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
Fasiglifam SCHEMBL29360096 0.89 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3
Fasiglifam SCHEMBL204652 0.89 FFAR1 (1.00) FFAR1GNA15SLC10A1ABCC2SLCO1B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014146604-A1 FUSED RING COMPOUND HAVING GPR40 RECEPTOR FUNCTION REGULATING ACTION 正大天晴药业集团股份有限公司 (CN) 2014-09-25 WO disclosed