Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.68 |
| ▸ | PPARA | Q07869 | 1/20 | 0.64 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16125461 | 0.95 | PPARG (0.61) | PPARGPPARAAGTR1 | |
| SCHEMBL16125521 | 0.90 | PPARG (0.56) | PPARGPPARAAGTR1 | |
| SCHEMBL16125412 | 0.90 | PPARG (0.72) | PPARGPPARAAGTR1 | |
| SCHEMBL16125460 | 0.90 | PPARG (0.72) | PPARGPPARAAGTR1 | |
| SCHEMBL16125414 | 0.89 | PPARG (0.69) | PPARGPPARAAGTR1 | |
| SCHEMBL16125463 | 0.86 | PPARG (0.70) | PPARG | |
| SCHEMBL16125440 | 0.84 | PPARG (0.64) | PPARGPPARAAGTR1 | |
| SCHEMBL16125518 | 0.84 | PPARG (0.48) | PPARGPPARAAGTR1 | |
| SCHEMBL16125441 | 0.83 | PPARG (0.66) | PPARG | |
| SCHEMBL14977804 | 0.83 | PPARG (0.73) | PPARGPPARAAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288090-A1 | N-ARYLYLMETHYLINDAZOLE MODULATORS OF PPARG | SCRIPPS RESEARCH INSTITUTE, THE | 2014-09-25 | — | — | US | disclosed |
| US-20140288090-A1 | N-ARYLYLMETHYLINDAZOLE MODULATORS OF PPARG | SCRIPPS RESEARCH INSTITUTE, THE | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288090-A1 | N-ARYLYLMETHYLINDAZOLE MODULATORS OF PPARG | CDK5, CDK5R1, PPARG | PPARG 3/4885PPARA 5/4885AGTR1 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.