Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098149 | 0.92 | TRPV1 (0.62) | MEN1KMT2AABCC1HDAC1HDAC8 | |
| SCHEMBL11592458 | 0.92 | KMT2A (0.69) | MEN1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL610530 | 0.92 | MEN1 (0.72) | MEN1KMT2ACYP3A4POLBALDH1A1 | |
| SCHEMBL29440797 | 0.92 | MEN1 (0.72) | MEN1KMT2ACYP3A4POLBALDH1A1 | |
| Nitrogen SCHEMBL28359211 | 0.89 | MEN1 (0.69) | MEN1KMT2ACYP3A4POLBALDH1A1 | |
| SCHEMBL6926258 | 0.85 | ABCC1 (0.76) | MEN1KMT2AABCC1HDAC1HDAC8 | |
| SCHEMBL17539221 | 0.85 | KMT2A (0.53) | MEN1KMT2AABCC1HDAC1PTPN1 | |
| SCHEMBL11147327 | 0.85 | POLB (0.63) | MEN1KMT2AHDAC1POLBALDH1A1 | |
| SCHEMBL17507452 | 0.85 | KMT2A (0.59) | MEN1KMT2APOLBALDH1A1NPC1 | |
| SCHEMBL6809736 | 0.85 | NPC1 (0.60) | MEN1KMT2AHDAC8CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| WO-2014147182-A2 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | AADAC, NAT1, CCNA1 | MEN1 901/4885KMT2A 336/4885ABCC1 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.