Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315465 | 0.78 | NOTUM (0.51) | NOTUMKDM4EGSK3BALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL5636567 | 0.77 | NOTUM (0.50) | NOTUMKDM4EGSK3BALDH1A1GAA | |
| SCHEMBL5637075 | 0.75 | NOTUM (0.45) | NOTUMBCHEKDM4EGSK3BGAA | |
| SCHEMBL4708088 | 0.74 | NOTUM (0.37) | NOTUMMAOABCHEACHEHSD17B3 | |
| Hydrochloric Acid SCHEMBL5638604 | 0.74 | NOTUM (0.44) | NOTUMBCHEKDM4EGSK3BALDH1A1 | |
| SCHEMBL5135034 | 0.73 | NOTUM (0.38) | NOTUMMAOABCHEACHEHSD17B3 | |
| SCHEMBL2513920 | 0.73 | NOTUM (0.42) | NOTUMMAOABCHEACHEHSD17B3 | |
| SCHEMBL627227 | 0.73 | MAOA (0.46) | NOTUMMAOABCHEHSD17B3KDM4E | |
| SCHEMBL4538011 | 0.73 | NOTUM (0.38) | NOTUMMAOABCHEACHEHSD17B3 | |
| SCHEMBL6096618 | 0.73 | NOTUM (0.42) | NOTUMMAOABCHEACHEHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329888-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | Amgen Inc. (US) | 2024-03-06 | — | — | EP | claimed |
| CN-108026105-A | Tgf beta receptor antagonists | 百时美施贵宝公司 | 2018-05-11 | — | — | CN | claimed |
| EP-2611907-A2 | DIFFERENTIATION OF PLURIPOTENT STEM CELLS | Janssen Biotech, Inc. (US) | 2013-07-10 | — | — | EP | claimed |
| WO-2012030540-A2 | DIFFERENTIATION OF PLURIPOTENT STEM CELLS | JANSSEN BIOTECH, INC. (US) | 2012-03-08 | — | — | WO | claimed |
| US-20250177359-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2025-06-05 | — | — | US | disclosed |
| EP-4469046-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | Oulun Yliopisto (FI) | 2024-12-04 | — | — | EP | disclosed |
| CN-112585136-B | Urea compounds and compositions as SMARCA2/BRM atpase inhibitors | 诺华股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-110719778-B | Compositions and methods for treating depression | 才思治疗公司 | 2024-06-18 | — | — | CN | disclosed |
| US-11958846-B2 | Urea compounds and compositions as SMARCA2/BRM ATPase inhibitors | NOVARTIS AG (CH) | 2024-04-16 | — | — | US | disclosed |
| EP-4329888-A1 | 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | Amgen Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023144450-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2023-08-03 | — | — | WO | disclosed |
| US-5358536-A | Dyestuff for heat-sensitive transfer record and transfer sheet containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0529600-A1 | Process for the preparation of 2-aminobenzothiazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-03 | — | — | EP | disclosed |
| EP-0526170-A2 | Dyestuff for heat-sensitive transfer record and transfer sheet containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-4988605-A | Heat and chemical resistant polymers for printed circuits | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0028406-A1 | Copolymerizable, ultraviolet light absorber N-benzothiazoloazines | GAF CORPORATION (US) | 1981-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11958846-B2 | Urea compounds and compositions as SMARCA2/BRM ATPase inhibitors | SMARCC1, SMARCC2, SMARCA1 | NOTUM 4132/4885MAOA 3483/4885BCHE 1458/4885 |
| US-20250177359-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | NAMPT, NADK, NQO1 | NOTUM 1798/4885MAOA 475/4885BCHE 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.