Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129751 | 0.88 | TACR1 (0.41) | TACR1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16099435 | 0.81 | TACR1 (0.44) | TACR1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16100235 | 0.80 | TACR1 (0.46) | TACR1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL3555080 | 0.79 | MAPT (0.49) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL16099909 | 0.77 | TACR1 (0.42) | TACR1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16094218 | 0.77 | TACR1 (0.45) | TACR1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16099088 | 0.76 | TACR1 (0.41) | TACR1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16099607 | 0.76 | TACR1 (0.41) | TACR1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16094402 | 0.74 | TACR1 (0.42) | TACR1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16101985 | 0.74 | ENPP2 (0.43) | TACR1MEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152725-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-09-25 | — | — | WO | disclosed |