Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099873 | 0.91 | TACR1 (0.40) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16129719 | 0.89 | ENPP2 (0.40) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16100235 | 0.87 | TACR1 (0.46) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16094402 | 0.85 | TACR1 (0.42) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16129768 | 0.81 | ENPP2 (0.39) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16099611 | 0.81 | ENPP2 (0.40) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16129819 | 0.81 | ENPP2 (0.41) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16101985 | 0.81 | ENPP2 (0.43) | TACR1ENPP2KMT2AKCNH2MEN1 | |
| SCHEMBL16099642 | 0.80 | TACR1 (0.39) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16102646 | 0.80 | ENPP2 (0.42) | TACR1ENPP2KMT2AKCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152725-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-09-25 | — | — | WO | disclosed |