Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099381 | 0.94 | TACR1 (0.38) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16102274 | 0.91 | TACR1 (0.42) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16100336 | 0.90 | TACR1 (0.41) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16099971 | 0.88 | TACR1 (0.40) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16129760 | 0.88 | TACR1 (0.38) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16129764 | 0.87 | TACR1 (0.40) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16100235 | 0.87 | TACR1 (0.46) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16129885 | 0.87 | TACR1 (0.38) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16129747 | 0.87 | HDAC6 (0.41) | TACR1ENPP2HTR2AABATSIGMAR1 | |
| SCHEMBL16129834 | 0.86 | ENPP2 (0.39) | TACR1ENPP2HTR2AABATSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152725-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-09-25 | — | — | WO | disclosed |